Bern Center for Precision Medicine (BCPM)

Projects: 2nd round

The goal of the 2nd call  was to select precision medicine projects that would address two areas defined by the BCPM:

  • Reproducibility in Biomedical Research
  • Integrating Data from Multiple Platforms for Precision Medicine

The eight projects selected for funding are listed below.

Reproducibility in Biomedical Research

Topic: Pneumology

Individual fibrinolytic potential in patients with acute pulmonary embolism undergoing ultrasound assisted catheter directed thrombolysis

Dominik F. Draxler

Topic: Infectious Diseases

Optimization of nanopore-based sequencing for bloodstream infection diagnostics

Alban Ramette

Integrating Data from Multiple Platforms for Precision Medicine

Topic: Cardiology

Flow-dependency of aortic valve opening: development of a precise diagnostic tool for patients with low-flow, low-gradient aortic stenosis

Eric Buffle

Topic: Neurology

Advancing human pluripotent stem cell derived in vitro brain barrier models to investigate the pathogenesis of multiple sclerosis

Britta Engelhardt

Topic: Pharmacology

PGXLink PGM (PharmacoGenoMetabolomics)

Alexander Leichtle

Topic: Cardiology

Precision Rhythmology – Identification of disease-modifiers for personalized risk stratification and therapy in genetic arrhythmia disorders

Katja Odening

Topic: Hepatology

Single cell analysis for non-invasive biomarker discovery for NASH patients using both protein and transcriptome analysis

Deborah Stroka

Topic: Pharmacology

Functional glycomics - patient immunoprofiles in cancer

Stephan von Gunten