Projects: 1st round
The goal of this 1st round call was to support innovative translational research projects that address key challenge areas in Precision Medicine, with a special focus on the usage of Next Generation Sequencing (NGS). The following seven projects were selected:
Topic: Hepatology
Predictive factors of cirrhosis regression in patients with advanced chronic liver disease
Annalisa Berzigotti
Topic: Oncology
Preclinical development of an adoptive T cell therapy strategy to treat patients with non-small cell lung cancer
Sean Hall
Topic: Oncology
NMIBC a personalized approach: defining the genomic landscape and response to therapy
Marianna Kruithof-de Julio
Topic: Gastroenterology
A pilot project to define microbiota bottlenecks using the trajectory of subspecies clade allele frequencies through high-definition personalized analysis in individual Crohn’s disease patients and controls
Andrew J. Macpherson
Topic: Gynecology and Obstetrics
Whole genome sequencing and single cell transcriptome analysis of progestin resistance in endometriosis
Konstantinos Nirgianakis
Topic: Oncology
Targeting the niche of drug-tolerant tumor-repopulating cells to eradicate residual disease in breast cancer
Sven Rottenberg
Topic: Dermatology
DisSECt Disease modelling in Skin Explant Cultures
Christoph Schlapbach